CD14 antibody (MEM-15) (PE-DyLight 594)

Clone Name: MEM-15

Application Note: FACS: 4 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 40

Specificity/Sensitivity: This antibody reacts with CD14, a 53-55 kDa GPI (glycosylphosphatidylinositol)-linked membrane glycoprotein expressed on monocytes, macrophages and weakly on granulocytes; also expressed by most tissue macrophages. And this antibody also reacts with soluble forms of CD14 found in serum and in the urine of some nephrotic patients.

Form: Liquid

Buffer (with preservative): PBS, 15mM Sodium azide.

Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010]

Uniprot ID: P08571

Antigen Species: Human

Immunogen: A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria.

Purification: Purified by size-exclusion chromatography

Conjugation: PE-DyLight 594

Full Name: CD14 molecule