CD18 antibody (MEM-48) (Low Endotoxin)

Clone Name: MEM-48

Calculated MW: 85

Specificity/Sensitivity: This antibody recognizes an epitope involving residues 534-546 in cysteine-rich repeat 3 of the CD18 antigen (integrin beta2 subunit; beta2 integrin).,We do not recommend use of this product for Dog.

Form: Liquid

Buffer (with preservative): 0.2μm filter-sterilized PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Uniprot ID: P05107

Antigen Species: Human

Immunogen: Leukocytes of a patient suffering from a LGL-type leukemia.

Purification: Protein A purified

Conjugation: Unconjugated

Full Name: integrin subunit beta 2