EGFR antibody (GFR/2341)

Clone Name: GFR/2341

Light Chain: Kappa

Application Note: IHC-P: 1-2μg/ml for 30 minutes at RT. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 134

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA, 0.05% Sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]

Uniprot ID: P00533

Antigen Species: Human

Immunogen: Recombinant fragment of human EGFR protein (around aa 344-492) (exact sequence is proprietary)

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: epidermal growth factor receptor