Kappa Opioid Receptor antibody

Clone Name:

Calculated MW: 43

Form: Liquid

Buffer (with preservative): PBS pH7.4, 1% BSA, 0.05% Sodium azide.

Concentration: 0.8 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]

Uniprot ID: P34975

Antigen Species: Rat

Immunogen: Peptide (C)NGSVGSEDQQLEPAHIS, corresponding to amino acid residues 39-55 of rat κ-Opioid receptor (Accession P34975). Extracellular, N-terminus.

Purification: Purified by antigen-affinity chromatography

Conjugation: Unconjugated

Full Name: opioid receptor, kappa 1