Melanoma gp100 antibody (PMEL/2038)

Melanoma gp100 antibody (PMEL/2038)
Artikelnummer
GTX17773-100
Verpackungseinheit
100 μg
Hersteller
GeneTex

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Clone Name: PMEL/2038

Light Chain: Kappa

Application Note: IHC-P: 1-2μg/ml for 30 minutes at RT. ELISA: 2-4μg/ml (for coating). *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 70

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA, 0.05% Sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]

Uniprot ID: P40967

Antigen Species: Human

Immunogen: A recombinant fragment (around aa 376-502) of human SILV protein (exact sequence is proprietary)

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: premelanosome protein
Mehr Informationen
Artikelnummer GTX17773-100
Hersteller GeneTex
Hersteller Artikelnummer GTX17773-100
Verpackungseinheit 100 μg
Mengeneinheit STK
Reaktivität Human
Klonalität Monoclonal
Methode Immunohistochemistry (paraffin), ELISA, Protein Array
Isotyp IgG1
Human Gene ID 6490
Wirt Mouse
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