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Acetylated Lysine Antibody: Dylight 488, Monoclonal

Acetylated Lysine Antibody: Dylight 488, Monoclonal
354,24 €
Artikelnummer: STRSMC-153D-DY488

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
Acetylated Lysine Antibody: Dylight 488, Monoclonal, Clone: 7F8, Host: Mouse, Isotype: IgG1

Details

Mouse Anti- Acetylated Lysine Monoclonal IgG1
Target: Acetylated Lysine
Purification: Protein G Purified
Specificity: Detects proteins containing acetylated lysine residues in ELISA and western blots. Does not detect non-acetylated lysine residues.
Conjugate: Dylight 488
Cellular Location: Nucleus
Immunogen: Acetylated KLH
Scientific Background: Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways, and a common post-transcriptional modification of Lysine involves acetylation (1). The conserved amino-terminal domains of the four core histones (H2A, H2B, H3 and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs) (2). Protein posttranslational reversible lysine Nε development (5).
Reference: 1. Yang XJ. (2005). Oncogene. 24:1653-1662.2. Hassig, C.A. and Schreiber, S.L. (1997). Curr. Opin. Chem. Biol. 1(3): 300-308.3. Yang XJ. (2004). Bioessays 26:1076-1087.4. Hughes, R.E. (2002). Curr. Biol. 12: R141-R143.5. Vigushin, D.M. and Coombes, R.C. (2004). Curr. Cancer Drug Targets 4: 205-218.

Zusatzinformation

Artikelnummer STRSMC-153D-DY488
Hersteller Stressmarq Biosciences
Herstellernummer SMC-153D-DY488
Verpackungseinheit 100 µg
Mengeneinheit FL
Reaktivität Various species
Klonalität Monoclonal
Wirt / Host Mouse
Methode ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
Isotype IgG1
Gene ID Keine Herstellerangabe
Datenblatt Download
MSDS Download