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Mouse Anti-Human DUX4 Monoclonal IgG1 Dylight 405

Mouse Anti-Human DUX4 Monoclonal IgG1 Dylight 405
348,99 €
Artikelnummer: STRSMC-192D-DY405

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
Mouse Anti-Human DUX4 Monoclonal IgG1 Dylight 405, Clone: P2B1

Details

DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1 (1). Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function (2-4). In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues (5).

1 µg/ml of SMC-192 was sufficient for detection of DUX4 in 20 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-mouse IgG: HRP as teh secondary.

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Zusatzinformation

Artikelnummer STRSMC-192D-DY405
Hersteller Stressmarq Biosciences
Herstellernummer SMC-192D-DY405
Verpackungseinheit 100 µg
Mengeneinheit FL
Reaktivität Human, Mouse (Murine)
Klonalität Monoclonal
Wirt / Host Mouse
Methode Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blotting
Isotype IgG
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download