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EndoPDI Antibody: Dylight 633, Monoclonal

EndoPDI Antibody: Dylight 633, Monoclonal
351,06 €
Artikelnummer: STRSMC-204D-DY633

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

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EndoPDI Antibody: Dylight 633, Monoclonal, Clone: 2E7/7, Host: Mouse, Isotype: IgG2a

Details

Mouse Anti-Human EndoPDI Monoclonal IgG2a
Target: PDI
Purification: Protein G Purified
Specificity: Detects ~48kDa.
Conjugate: Dylight 633
Immunogen Species: Human
Cellular Location: Endoplasmic Reticulum, Endoplasmic Reticulum Lumen
Immunogen: Synthesized peptide - 12 amino acids long (ADGEDGQDPHSK) corresponding to residues 52 - 63 of the EndoPDI protein
Scientific Background: Endothelial protein disulfide isomerase (EndoPDI) is a thioredoxin member of the protein disulfide isomerase family of chaperones. This enzyme has been localized to the endoplasmic reticulum in primary endothelial cells, but colocalizes with nucleoli in the nuclei of breast, colon, and renal cancer cells. EndoPDI mRNA and protein expression is induced by hypoxia and exhibits a protective effect on endothelial cells during hypoxia (1).
Reference: 1. Sullivan D.C., et al. (2003) J Biol Chem. 278 (47) 47079-47088.

Zusatzinformation

Artikelnummer STRSMC-204D-DY633
Hersteller Stressmarq Biosciences
Herstellernummer SMC-204D-DY633
Verpackungseinheit 100 µg
Mengeneinheit FL
Reaktivität Human
Klonalität Monoclonal
Wirt / Host Mouse
Methode ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
Isotype IgG2
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download