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Mouse Anti-Human Histone H3 (tri Methyl Lys79) Monoclonal IgG1  Dylight 350

Mouse Anti-Human Histone H3 (tri Methyl Lys79) Monoclonal IgG1  Dylight 350
384,49 €
Artikelnummer: STRSMC-253D-DY350

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
Mouse Anti-Human Histone H3 (tri Methyl Lys79) Monoclonal IgG1  Dylight 350, Clone: 5D8

Details

Histone H3 is a 17 kD nuclear protein that is a component of an octamer containing pairs of each of four core histones (H2A, H2B, H3, H4). The core histones create nucleosome structure of chromosomal fiber in eukaryotes and are dynamic in gene regulation. The histones exhibit cell cycle-dependent transcriptional regulation except for the variant H3.3 which is cell cycle-independent. Histone H3 can be modified by phosphorylation, acetylation, ubiquitination, ribosylation, and methylation. Histone H3 has been shown to interact with Rsk-2, MSK1, GCN5 family of HATs, HDACs, PARP, SET7/9, and CARM1. Histones play a cental role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

A 1:1000 dilution of SMC-253 was sufficient for detection of Histone H3 in 10 µg of Human HeLa cell lysates by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary antibody.

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Zusatzinformation

Artikelnummer STRSMC-253D-DY350
Hersteller Stressmarq Biosciences
Herstellernummer SMC-253D-DY350
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human, Mouse (Murine), Rat (Rattus)
Klonalität Monoclonal
Wirt / Host Mouse
Methode Western Blotting
Isotype IgG
Gene ID Nein
Datenblatt Download
MSDS Download