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Mouse Anti-Human LC3C Monoclonal IgG1 Dylight 350

Mouse Anti-Human LC3C Monoclonal IgG1 Dylight 350
352,03 €
Artikelnummer: STRSMC-212A-DY350

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
Mouse Anti-Human LC3C Monoclonal IgG1 Dylight 350, Clone: VB2

Details

Light chain 3 (LC3) is a microtubule-associated protein with an approximate molecular mass of 17kDa, and can be found ubiquitously throughout mammalian tissue. LC3 plays a role in autophagy; once the autophagic process is initiated in a cell, LC3 is conjugated to phosphatidylethanolamine to form LC3-II. This molecule is recruited to the autophagosome at the time of fusion with lysosomes, and LC3-II in autolysosomal lumen is degraded. Therefore, monitoring LC3 is an important tool for detecting autophagy and autophagy-related processes. LC3C is one of three isoforms which exhibits the lowest expression relative to the other two isoforms. Its highest expression is seen in placenta, lung and ovary.

A 1:20000 dilution of SMC-212 was sufficient for detection of LC3C in lysate from cells expressing recombinant GST-tagged LC3C by electrochemiluminescence analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Zusatzinformation

Artikelnummer STRSMC-212A-DY350
Hersteller Stressmarq Biosciences
Herstellernummer SMC-212A-DY350
Verpackungseinheit 50 µg
Mengeneinheit FL
Reaktivität Human, Mouse (Murine), Rat (Rattus)
Klonalität Monoclonal
Wirt / Host Mouse
Methode Immunoprecipitation, Western Blotting
Isotype IgG
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download