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PP5 Antibody: Dylight 488, Monoclonal

PP5 Antibody: Dylight 488, Monoclonal
355,30 €
Artikelnummer: STRSMC-243D-DY488

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

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PP5 Antibody: Dylight 488, Monoclonal, Clone: 2E11, Host: Mouse, Isotype: IgG2a

Details

Mouse Anti-Human PP5 Monoclonal IgG2a
Target: PP5
Purification: Protein G Purified
Specificity: Detects ~58kDa.
Conjugate: Dylight 488
Immunogen Species: Human
Cellular Location: Nucleus, Cytoplasm
Immunogen: Full length human PP5 protein
Scientific Background: Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues, potentially playing a role in the regulation of cell growth and differentiation. PP5 or PPT is predominantly a nuclear protein and interacts with CDC16 and CDC27. It is found in association with several proteins that influence intracellular signlaing-cascades intitiated by hormones (glucocorticoids) or cellular stress (hypoxia, oxidative stress and DNA Damage). It phosphorylates serine residues of skeletal muscle phosphorylase and histone H1. It may also be involved in mitosis and RNA biogenesis regulation (1,2).
Reference: 1. Butzow R., et al. (1988) J Lab Clin Med. 111(2): 249-256.

Zusatzinformation

Artikelnummer STRSMC-243D-DY488
Hersteller Stressmarq Biosciences
Herstellernummer SMC-243D-DY488
Verpackungseinheit 100 µg
Mengeneinheit FL
Reaktivität Human
Klonalität Monoclonal
Wirt / Host Mouse
Methode Immunocytochemistry, Immunofluorescence, Western Blotting
Isotype IgG2
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download