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SNAP-25 Antibody: Dylight 633, Monoclonal

SNAP-25 Antibody: Dylight 633, Monoclonal
318,18 €
Artikelnummer: STRSMC-180D-DY633

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
SNAP-25 Antibody: Dylight 633, Monoclonal, Clone: SP-12, Host: Mouse, Isotype: IgG1

Details

Mouse Anti-Human SNAP-25 Monoclonal IgG1
Target: SNAP25
Purification: Protein G Purified
Specificity: Detects ~29kDa.
Conjugate: Dylight 633
Immunogen Species: Human
Cellular Location: Cytoplasm
Immunogen: Raised against a crude synaptic preparation from the post mortem human brain
Scientific Background: Synaptosomal-associated protein 25 (SNAP-25) is a membrane bound protein anchored to the cytosolic face of membrane via palmitoyl side chains in the middle of the molecule (1). It is a component of the SNARE complex, which is proposed to account for the specificity of membrane fusion and to directly execute fusion by forming a tight complex that brings the synaptic vesicle and plasma membranes together (2).SNAP25 exists as two alternatively spliced isoforms, SMAP25A and SNAP25B. These isoforms are differentially expressed in neurons and neuroendocrine cells and they differ by 9 amino acids in the central portion of the protein (3).
Reference: 1. Hodel A. (1998) Int J. Biochem Cell Biol. 30(10): 1069-1073.2. Sudhof T.C., and Rizo J. (2002) Nat Rev Neurosci. 3(8): 641-653.3. Puffer E.B., et al. (2001) Biochemistry. 40(31): 9374-9378.

Zusatzinformation

Artikelnummer STRSMC-180D-DY633
Hersteller Stressmarq Biosciences
Herstellernummer SMC-180D-DY633
Verpackungseinheit 100 µg
Mengeneinheit FL
Reaktivität Cat (Feline), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
Klonalität Monoclonal
Wirt / Host Mouse
Methode ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blotting
Isotype IgG1
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download