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Trap1 Antibody: Dylight 350, Monoclonal

Trap1 Antibody: Dylight 350, Monoclonal
355,30 €
Artikelnummer: STRSMC-193D-DY350

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
Trap1 Antibody: Dylight 350, Monoclonal, Clone: Trap1-6, Host: Mouse, Isotype: IgG2a

Details

Mouse Anti-Human Trap1 Monoclonal IgG2a Kappa
Target: TRAP1
Purification: Protein G Purified
Specificity: Detects ~75kDa.
Conjugate: Dylight 350
Immunogen Species: Human
Cellular Location: Mitochondrion
Immunogen: Purified recombinant full length TRAP1 (no tags)
Scientific Background: The 90 kDa heat shock protein (HSP90) family of proteins that play an important physiological role. HSP90 is involved in numerous cellular processes but is best known for its association with signal transduction machinery. A recently cloned homolog of HSP90 is the tumor necrosis factor receptor-associated protein (TRAP1). Like HSP90, TRAP1 is found to be associated with numerous proteins involved in diverse actions (1, 2). Immunofluorescence data has shown TRAP1 to be localized in the mitochondria of mammalian cells. This observation and the fact that TRAP1 is shown to have a mitochondrial targeting pre-sequence strongly implicates TRAP1 as a mitochondrial matrix protein (3).
Reference: 1. Felts S.J., et al. (2000) J Biol Chem. 275(5): 3305-3312.2. Costantino E., et al. (2009) Cancer Lett. 279(1): 39-46.3. Cechetto J.D., Gupta R.S. (2000) Exp Cell Res. 260(1): 30-39.

Zusatzinformation

Artikelnummer STRSMC-193D-DY350
Hersteller Stressmarq Biosciences
Herstellernummer SMC-193D-DY350
Verpackungseinheit 100 µg
Mengeneinheit FL
Reaktivität Human
Klonalität Monoclonal
Wirt / Host Mouse
Methode Immunocytochemistry, Immunofluorescence, Western Blotting
Isotype IgG2
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download