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VAMP1/2 Antibody: Dylight 488, Monoclonal

VAMP1/2 Antibody: Dylight 488, Monoclonal
299,09 €
Artikelnummer: STRSMC-179D-DY488

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
VAMP1/2 Antibody: Dylight 488, Monoclonal, Clone: SP-11, Host: Mouse, Isotype: IgG1

Details

Mouse Anti-Human VAMP1/2 Monoclonal IgG1
Target: VAMP
Purification: Protein G Purified
Specificity: Detects ~20-25kDa. Recognizes VAMP 1 and 2.
Conjugate: Dylight 488
Immunogen Species: Human
Cellular Location: Mitochondrion, Mitochondrion Outer Membrane, Cytoplasmic Vesicle
Immunogen: Crude human synaptic immunoprecipitate
Scientific Background: VAMP-1, also known as vesicle-associated membrane protein, is an 18kDa member of the synaptobrevin family of proteins. It is expressed in neurons, neutrophils, and skeletal muscle cells, and participates in vesicle fusion with the plasma membrane (1). Synaptobrevins, Syntakins and the 25kDa synaptosomal associated SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane (2). VAMP-1 is also one of the key proteins in the SNARE complex which is involved in regulated exocytosis (3).
Reference: 1. Trimble W.S., Cowan D.M., and Scheller R.H. (1988) Proc Natl Acad Sci USA. 85: 4538-4542.2. Nabokina S.M. (2001) Bulletin of Experimental Bio and Med. 131(2): 130-131.3. Berglund L., Hoffman H.J., Dahl R., and Peterson T.E. (1999) Biochem Biophys Research Communicaitons. 264(3): 777-780.

Zusatzinformation

Artikelnummer STRSMC-179D-DY488
Hersteller Stressmarq Biosciences
Herstellernummer SMC-179D-DY488
Verpackungseinheit 100 µg
Mengeneinheit FL
Reaktivität Human, Rat (Rattus)
Klonalität Monoclonal
Wirt / Host Mouse
Methode ELISA, Immunohistochemistry, Western Blotting
Isotype IgG1
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download