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Mouse Anti- Phosphotyrosine Monoclonal IgG1 Kappa Dylight 633

Mouse Anti- Phosphotyrosine Monoclonal IgG1 Kappa Dylight 633
304,35 €
Artikelnummer: STRSMC-157D-DY633

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
Mouse Anti- Phosphotyrosine Monoclonal IgG1 Kappa Dylight 633, Clone: 13F9

Details

Protein phosphorylation is an important posttranslational modification that serves many key functions to regulate a protein's activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently attaching it to to a recipient protein that acts as a substrate. Most kinases act on both serine and threonine; others act on tyrosine, and a number (dual specificity kinases) act on all three. Because phosphorylation can occur at multiple sites on any given protein, it can therefore change the function or localization of that protein at any time (1). Changing the function of these proteins has been linked to a number of diseases, including cancer, diabetes, heart disease, inflammation and neurological disorders (2-4).In particular, the phosphorylation of tyrosine is considered one of the key steps in signal transduction and regulation of enzymatic activity (5). Phosphotyrosine can be detected through specific antibodies, and are helpful in facilitating the identification of tyrosine kinase substrates (6).

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Zusatzinformation

Artikelnummer STRSMC-157D-DY633
Hersteller Stressmarq Biosciences
Herstellernummer SMC-157D-DY633
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Various species
Klonalität Monoclonal
Wirt / Host Mouse
Methode ELISA, Immunocytochemistry, Immunofluorescence, Western Blotting
Isotype IgG
Gene ID Nein
Datenblatt Download
MSDS Download