PLK1 (phospho Tyr217) antibody

Clone Name:

Application Note: WB: 1:500-1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 68

Form: Liquid

Buffer (with preservative): PBS pH7.4, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy. [provided by RefSeq, Sep 2015]

Uniprot ID: P53350

Antigen Species: Human

Immunogen: A synthesized peptide derived from human PLK1 around the phosphorylation site of Tyr217

Purification: Purified by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns

Conjugation: Unconjugated

Full Name: polo like kinase 1