PU.1 antibody (PU1/2146)

Clone Name: PU1/2146

Light Chain: Kappa

Application Note: WB: 1-2μg/ml. ICC/IF: 1-2μg/ml. IHC-P: 1-2μg/ml for 30 minutes at RT. FACS: 1-2μg/10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 31

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA, 0.05% Sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot ID: P17947

Antigen Species: Human

Immunogen: Recombinant fragment (around aa 16-170) of human PU.1 protein (Exact sequence is proprietary)

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: Spi-1 proto-oncogene