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Abl2 Antibody (pTyr439 + pThr440): Dylight 350, Polyclonal

Abl2 Antibody (pTyr439 + pThr440): Dylight 350, Polyclonal
444,39 €
Artikelnummer: STRSPC-906D-DY350

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

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Abl2 Antibody (pTyr439 + pThr440): Dylight 350, Polyclonal, Host: Rabbit

Details

Rabbit Anti-Human Abl2 (pTyr439 + pThr440) Polyclonal
Target: Abl2 (pTyr439 + pThr440)
Purification: Peptide Affinity Purified
Specificity: Detects 128.343 kDa.
Tissue Specificity: Widely expressed
Conjugate: Dylight 350
Immunogen Species: Human
Cellular Location: Cytoplasm, Cytoskeleton
Immunogen: A phospho-specific peptide corresponding to residues surrounding Tyr439 and Thr440 of human Abl2 (AA3437-443)
Scientific Background: ABL2 (Arg) is a widely expressed, 128 kDa, non-receptor protein-tyrosine kinases that is structurally related to Abl1. It features SH3 and SH2 domains, a protein- tyrosine kinase domain, and a nuclear localization domain. It shares many functions with Abl1, which includes cytoskeleton remodelling through phosphorylation of enzymes responsible for cytoskeleton rearrangements for signalling, adhesion, and movement as well as microtuble subunits, TUBA1 and TUBB. It also contains F-actin binding region to bundle and regulate actin cytoskeletal structure. It possesses autocatalytic activity and the ability to phosphorylate its inhibitor ABI1 to regulate itself.

Zusatzinformation

Artikelnummer STRSPC-906D-DY350
Hersteller Stressmarq Biosciences
Herstellernummer SPC-906D-DY350
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download