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Rabbit Anti-Human Abl2 (pTyr439 + pThr440) Polyclonal Dylight 633

Rabbit Anti-Human Abl2 (pTyr439 + pThr440) Polyclonal Dylight 633
374,35 €
Artikelnummer: STRSPC-906D-DY633

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

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Rabbit Anti-Human Abl2 (pTyr439 + pThr440) Polyclonal Dylight 633

Details

ABL2 (Arg) is a widely expressed, 128 kDa, non-receptor protein-tyrosine kinases that is structurally related to Abl1. It features SH3 and SH2 domains, a protein- tyrosine kinase domain, and a nuclear localization domain. It shares many functions with Abl1, which includes cytoskeleton remodelling through phosphorylation of enzymes responsible for cytoskeleton rearrangements for signalling, adhesion, and movement as well as microtuble subunits, TUBA1 and TUBB. It also contains F-actin binding region to bundle and regulate actin cytoskeletal structure. It possesses autocatalytic activity and the ability to phosphorylate its inhibitor ABI1 to regulate itself.

A 1:250 dilution of SPC-906 was sufficient for detection of Abl2 (pTyr439 + pThr440) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Zusatzinformation

Artikelnummer STRSPC-906D-DY633
Hersteller Stressmarq Biosciences
Herstellernummer SPC-906D-DY633
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download