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ALK Antibody (pTyr1507): Dylight 633, Polyclonal

ALK Antibody (pTyr1507): Dylight 633, Polyclonal
391,36 €
Artikelnummer: STRSPC-913D-DY633

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
ALK Antibody (pTyr1507): Dylight 633, Polyclonal, Host: Rabbit

Details

Rabbit Anti-Human ALK (pTyr1507) Polyclonal
Target: ALK (pTyr1507)
Purification: Peptide Affinity Purified
Specificity: Detects 176.428 kDa.
Tissue Specificity: Expressed in brain and CNS. Also expressed in the small intestine and testis, but not in normal lymphoid cells
Conjugate: Dylight 633
Immunogen Species: Human
Cellular Location: Membrane
Immunogen: A phospho-specific peptide corresponding to residues surrounding Tyr1507 of human ALK (AA374-382)
Scientific Background: ALK is a receptor-tyrosine kinase (belonging to the insulin receptor family) that is activated upon binding an unidentified ligand. Chromosomal rearrangments (most common), mutations, and amplifications in this gene are associated with numerous tumours including: anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. These fusion proteins, as well as other mutations and amplifications, likely confer hightened (possibly consititutive) kinase activity and thus promote cell growth and anti-apoptotic pathways such as the Akt MAPK pathways.

Zusatzinformation

Artikelnummer STRSPC-913D-DY633
Hersteller Stressmarq Biosciences
Herstellernummer SPC-913D-DY633
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download