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ATR Antibody (pSer435 + pSer436): Dylight 350, Polyclonal

ATR Antibody (pSer435 + pSer436): Dylight 350, Polyclonal
444,39 €
Artikelnummer: STRSPC-918D-DY350

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

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ATR Antibody (pSer435 + pSer436): Dylight 350, Polyclonal, Host: Rabbit

Details

Rabbit Anti-Human ATR (pSer435 + pSer436) Polyclonal
Target: ATR (pSer435 + pSer436)
Purification: Peptide Affinity Purified
Specificity: Detects 301.367 kDa.
Tissue Specificity: Ubiquitous
Conjugate: Dylight 350
Immunogen Species: Human
Cellular Location: Nucleus, PML body
Immunogen: A phospho-specific peptide corresponding to residues surrounding Ser435 and Ser436 of human ATR (AA432-439)
Scientific Background: ATR is a protein-serine/threonine kinase. It is part of the PI3K family and functions in a complex with ATRIP. It responds to DNA damage and replication stresses and activates proteins that mediate DNA repair such as p53, BRCA1 and more. It other roles involve checkpoint signalling by interacting with chk1, fragile site stabilty and regulation of centrosome duplication.

Zusatzinformation

Artikelnummer STRSPC-918D-DY350
Hersteller Stressmarq Biosciences
Herstellernummer SPC-918D-DY350
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download