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Rabbit Anti-Human Aurora A (pThr287 + pThr288) Polyclonal Dylight 405

Rabbit Anti-Human Aurora A (pThr287 + pThr288) Polyclonal Dylight 405
400,72 €
Artikelnummer: STRSPC-919D-DY405

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
Rabbit Anti-Human Aurora A (pThr287 + pThr288) Polyclonal Dylight 405

Details

Aurora A is part of the larger AURA family of serine/threonine kinases and is a key regulator of mitotic cell division. It is involved in regulating microtubule formation and the assembly of the mitotic spindle responsible for chromosome segragation during mitosis. AURA activity is cell cycle dependent with the greatest activity occuring during mitosis. The overexpression of AURA has been well documented in many malignant cancers including breast, ovarian, colon, prostate and neuroblastomas. Overexpression of AURA appears to override checkpoints in cell cycle progression leading to increased cell division and proliferation.

A 1:250 dilution of SPC-919 was sufficient for detection of Aurora A (pThr287 + pThr288) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Zusatzinformation

Artikelnummer STRSPC-919D-DY405
Hersteller Stressmarq Biosciences
Herstellernummer SPC-919D-DY405
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download