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BRK Antibody (pSer446 + pTyr447): Dylight 405, Polyclonal

BRK Antibody (pSer446 + pTyr447): Dylight 405, Polyclonal
418,94 €
Artikelnummer: STRSPC-926D-DY405

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

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BRK Antibody (pSer446 + pTyr447): Dylight 405, Polyclonal, Host: Rabbit

Details

Rabbit Anti-Human BRK (pSer446 + pTyr447) Polyclonal
Target: BRK (pSer446 + pTyr447)
Purification: Peptide Affinity Purified
Specificity: Detects 51.834 kDa.
Conjugate: Dylight 405
Immunogen Species: Human
Cellular Location: Cytoplasm, Nucleus
Immunogen: A phospho-specific peptide corresponding to residues surrounding Ser446 and Tyr447 of human BRK (AA443-450)
Scientific Background: BRK otherwise known as PTK6, is a protein-tyrosine kinase. It is a cytoplasmic nonreceptor protein-kinase that seems to function as an intracellular signal transducer in epithelial tissues. Upregulation of this gene in mammary epithelium causes sensitization to epidermal growth factor (EGF) and results in a partially transformed phenotype. Upregulation of this gene has been found in some breast cancers, while mutation in this gene have been found in skin, ovairan, and gastric tumours.

Zusatzinformation

Artikelnummer STRSPC-926D-DY405
Hersteller Stressmarq Biosciences
Herstellernummer SPC-926D-DY405
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download