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BRSK1 Antibody (pThr189): APC/Cy7, Polyclonal

BRSK1 Antibody (pThr189): APC/Cy7, Polyclonal
440,15 €
Artikelnummer: STRSPC-927D-APCCY7

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

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BRSK1 Antibody (pThr189): APC/Cy7, Polyclonal, Host: Rabbit

Details

Rabbit Anti-Human BRSK1 (pThr189) Polyclonal
Target: BRSK1 (pThr189)
Purification: Peptide Affinity Purified
Specificity: Detects 86.753 kDa.
Conjugate: APC/Cy7
Immunogen Species: Human
Cellular Location: Cytoplasm, Nucleus
Immunogen: A phospho-specific peptide corresponding to residues surrounding Thr189 of human BRSK1 (AA186-192)
Scientific Background: BRSK1 (BR serine/threonine-protein kinase 1), also known as SAD1, is a 794 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one UBA domain and one protein kinase domain. Expressed in a variety of tissues with highest expression in testis and brain, BRSK1 uses magensium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins, including Wee 1 and Cdc25B. Via its kinase activity toward proteins that are involved in microtubule assembly, BRSK1 plays an essential role in neuronal polarization and may be involved in regulating cell cycle arrest in response to DNA damage, Two isoforms of BRSK1 exist due to alternative splicing events.

Zusatzinformation

Artikelnummer STRSPC-927D-APCCY7
Hersteller Stressmarq Biosciences
Herstellernummer SPC-927D-APCCY7
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download