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BTK Antibody (pTyr223 + pTyr225): Dylight 633, Polyclonal

BTK Antibody (pTyr223 + pTyr225): Dylight 633, Polyclonal
391,36 €
Artikelnummer: STRSPC-928D-DY633

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

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BTK Antibody (pTyr223 + pTyr225): Dylight 633, Polyclonal, Host: Rabbit

Details

Rabbit Anti-Human BTK (pTyr223 + pTyr225) Polyclonal
Target: BTK (pTyr223 + pTyr225)
Purification: Peptide Affinity Purified
Specificity: Detects 76.281 kDa.
Conjugate: Dylight 633
Immunogen Species: Human
Cellular Location: Cytoplasm, Membrane, Nucleus
Immunogen: A phospho-specific peptide corresponding to residues surrounding Tyr223 and Tyr225 of human BTK (AA220-226)
Scientific Background: BTK is a cytoplasmic protein-tyrosine kinase, involved in B cell development, differentiation and signalling. It is a downstream target of the B-cell receptor and plays an important role in immune cell related pathways. BTK has a dual function in apoptosis. Not reported to directly interact with DNA. Expression of a truncated BTK variant in leukemia, which mediates phosphorylation and activation of normal BTK by BCR-ABL1. Constitutively activated BTK promotes cell survival.

Zusatzinformation

Artikelnummer STRSPC-928D-DY633
Hersteller Stressmarq Biosciences
Herstellernummer SPC-928D-DY633
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download