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Rabbit Anti-Human BubR1 (pSer670) Polyclonal APC/Cy7

Rabbit Anti-Human BubR1 (pSer670) Polyclonal APC/Cy7
421,01 €
Artikelnummer: STRSPC-929D-APCCY7

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
Rabbit Anti-Human BubR1 (pSer670) Polyclonal APC/Cy7

Details

BUBR1 is a protein-serine/threonine kinase. It is an essential component of mitotic checkpoint. It prevents progression of anaphase until all the sister chomatids are connected to spindles by binding to CDC20 to anaphase promoting complex/cycolsome thus inhibiting it. It is also involved in localization of CENPE, a kinetochore motor that performs kinetochore functions. Other functions include suppression of centrosome amplification, negative regulation of PLK1 in intephase and trigger apoptosis in polyploid cells.

A 1:250 dilution of SPC-929 was sufficient for detection of BubR1 (pSer670) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Zusatzinformation

Artikelnummer STRSPC-929D-APCCY7
Hersteller Stressmarq Biosciences
Herstellernummer SPC-929D-APCCY7
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download