• Sie sehen derzeit Listenpreise. Um Ihren Vorteilspreis zu sehen, melden Sie sich mit Ihrem Kundenkonto an.

BubR1 Antibody (pSer670): Dylight 633, Polyclonal

BubR1 Antibody (pSer670): Dylight 633, Polyclonal
391,36 €
Artikelnummer: STRSPC-929D-DY633

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
BubR1 Antibody (pSer670): Dylight 633, Polyclonal, Host: Rabbit

Details

Rabbit Anti-Human BubR1 (pSer670) Polyclonal
Target: BubR1 (pSer670)
Purification: Peptide Affinity Purified
Specificity: Detects 119 kDa.
Tissue Specificity: Highly expressed in thymus followed by spleen. Preferentially expressed in tissues with a high mitotic index.
Conjugate: Dylight 633
Immunogen Species: Human
Cellular Location: Cytoplasm, Nucleus
Immunogen: A phospho-specific peptide corresponding to residues surrounding Ser670 of human BUBR1 (AA667-673)
Scientific Background: BUBR1 is a protein-serine/threonine kinase. It is an essential component of mitotic checkpoint. It prevents progression of anaphase until all the sister chomatids are connected to spindles by binding to CDC20 to anaphase promoting complex/cycolsome thus inhibiting it. It is also involved in localization of CENPE, a kinetochore motor that performs kinetochore functions. Other functions include suppression of centrosome amplification, negative regulation of PLK1 in intephase and trigger apoptosis in polyploid cells.

Zusatzinformation

Artikelnummer STRSPC-929D-DY633
Hersteller Stressmarq Biosciences
Herstellernummer SPC-929D-DY633
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download