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CDK4 Antibody (pThr172): Dylight 594, Polyclonal

CDK4 Antibody (pThr172): Dylight 594, Polyclonal
401,97 €
Artikelnummer: STRSPC-943D-DY594

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

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CDK4 Antibody (pThr172): Dylight 594, Polyclonal, Host: Rabbit

Details

Rabbit Anti-Human CDK4 (pThr172) Polyclonal
Target: CDK4 (pThr172)
Purification: Peptide Affinity Purified
Specificity: Detects 33.73 kDa.
Conjugate: Dylight 594
Immunogen Species: Human
Cellular Location: Cytoplasm, Nucleus, Membrane
Immunogen: A phospho-specific peptide corresponding to residues surrounding Thr172 of human CDK4 (AA169-175)
Scientific Background: CDK4 is a protein-serine/threonine kinase, and a part of the protein kinase complex important for cell cycle G1 phase progression. Its activity is restricted to the G1-S phase. CDK4 is responsible for the phosphorylation of retinoblastoma gene product (Rb) and mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumourigenesis of a variety of cancers, such as cutaneous malignant melanoma type 3 (CMM3).

Zusatzinformation

Artikelnummer STRSPC-943D-DY594
Hersteller Stressmarq Biosciences
Herstellernummer SPC-943D-DY594
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download