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CrkRS Antibody (pSer383 + pSer385): APC/Cy7, Polyclonal

CrkRS Antibody (pSer383 + pSer385): APC/Cy7, Polyclonal
440,15 €
Artikelnummer: STRSPC-941D-APCCY7

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

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CrkRS Antibody (pSer383 + pSer385): APC/Cy7, Polyclonal, Host: Rabbit

Details

Rabbit Anti-Human CrkRS (pSer383 + pSer385) Polyclonal
Target: CrkRS (pSer383 + pSer385)
Purification: Peptide Affinity Purified
Specificity: Detects 164.155 kDa.
Conjugate: APC/Cy7
Immunogen Species: Human
Cellular Location: Nucleus
Immunogen: A phospho-specific peptide corresponding to residues surrounding Ser383 and Ser385 of human CrkRS (AA380-388)
Scientific Background: CrkRS (Cdc2-related kinase, arginine/serine-rich, also designated CRK7 and CRKR) is an ubiquitous protein that appears to localize to the nucleus and link transcription and splicing machinery. CrkRS belongs to the serine/threonine protein kinase family and Cdc2/Cdkx subfamily. CrkRS has extensive proline-rich regions that resemble SH3 and WW domain binding sites, and an RS domain that is characteristic of splicing factors. The protein kinase domain of CrkRS is 89% identical to the CHED protein kinase, also designated CDC2L5 and cell division cycle 2-like 5 (cholinesterase-related cell division controller), however outside the kinase domains the two proteins are unique. Cell cycle control kinases can phosphorylate proteins important for differentiation and apoptosis and provide connections between proliferation, differentiation, apoptosis, and neurocytoskeleton dynamics.

Zusatzinformation

Artikelnummer STRSPC-941D-APCCY7
Hersteller Stressmarq Biosciences
Herstellernummer SPC-941D-APCCY7
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download