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Rabbit Anti-Human DOK3 (pTyr398) Polyclonal APC/Cy7

Rabbit Anti-Human DOK3 (pTyr398) Polyclonal APC/Cy7
421,01 €
Artikelnummer: STRSPC-958D-APCCY7

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
Rabbit Anti-Human DOK3 (pTyr398) Polyclonal APC/Cy7

Details

DOK3 is a member of a class of “docking” proteins which contain multiple tyrosine residues and putative SH2 binding sites. DOK3 is an adapter involved in the recruitment of inhibitory molecules and is highly expressed in B cells and macrophages. Immunoreceptor-mediated cellular activation induces tyrosine phosphorylation of DOK3. Upon phosphorylation, DOK3 binds to 5' inositol phosphatase SHIP and the protein tyrosine kinase Csk. DOK3 may play a significant role in the negative regulation of immunoreceptor signaling in hemopoietic cells.

A 1:250 dilution of SPC-958 was sufficient for detection of DOK3 (pTyr398) in 10 µg of HepG2 cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Zusatzinformation

Artikelnummer STRSPC-958D-APCCY7
Hersteller Stressmarq Biosciences
Herstellernummer SPC-958D-APCCY7
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download