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DOK3 Antibody (pTyr398): Dylight 350, Polyclonal

DOK3 Antibody (pTyr398): Dylight 350, Polyclonal
444,39 €
Artikelnummer: STRSPC-958D-DY350

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

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DOK3 Antibody (pTyr398): Dylight 350, Polyclonal, Host: Rabbit

Details

Rabbit Anti-Human DOK3 (pTyr398) Polyclonal
Target: DOK3 (pTyr398)
Purification: Peptide Affinity Purified
Specificity: Detects 53.288 kDa.
Conjugate: Dylight 350
Immunogen Species: Human
Cellular Location: Cytoplasm, Cell Membrane
Immunogen: A phospho-specific peptide corresponding to residues surrounding Tyr397 of human EML4 (AA395-401)
Scientific Background: DOK3 is a member of a class of “docking” proteins which contain multiple tyrosine residues and putative SH2 binding sites. DOK3 is an adapter involved in the recruitment of inhibitory molecules and is highly expressed in B cells and macrophages. Immunoreceptor-mediated cellular activation induces tyrosine phosphorylation of DOK3. Upon phosphorylation, DOK3 binds to 5' inositol phosphatase SHIP and the protein tyrosine kinase Csk. DOK3 may play a significant role in the negative regulation of immunoreceptor signaling in hemopoietic cells.

Zusatzinformation

Artikelnummer STRSPC-958D-DY350
Hersteller Stressmarq Biosciences
Herstellernummer SPC-958D-DY350
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download