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EML4 Antibody (pTyr226): Dylight 350, Polyclonal

EML4 Antibody (pTyr226): Dylight 350, Polyclonal
444,39 €
Artikelnummer: STRSPC-964D-DY350

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

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EML4 Antibody (pTyr226): Dylight 350, Polyclonal, Host: Rabbit

Details

Rabbit Anti-Human EML4 (pTyr226) Polyclonal
Target: EML4 (pTyr226)
Purification: Peptide Affinity Purified
Specificity: Detects 108.903 kDa.
Conjugate: Dylight 350
Immunogen Species: Human
Cellular Location: Cytoskeleton
Immunogen: A phospho-specific peptide corresponding to residues surrounding Tyr226 of human EML4 (AA223-229)
Scientific Background: Echinoderm microtubule-associated (EML) proteins function to modify the assembly dynamics of microtubules. EML4 (Echinoderm microtubule-associated protein-like 4), also known as EMAPL4, ELP120, C2orf2 or ROPP120, is a 981 amino acid cytoplasmic protein that contains nine WD repeats. Expressed at high levels during mitosis, EML4 is thought to modify the assembly dynamics of microtubules, specifically altering microtubules to become longer and more flexible. Due to a chromosomal inversion with chromosome 2p, EML4 may exist as a fusion protein with ALK (anaplastic lymphoma receptor tyrosine kinase), producing an EML4-ALK fusion complex that plays a role in the pathogenesis of lung cancer.

Zusatzinformation

Artikelnummer STRSPC-964D-DY350
Hersteller Stressmarq Biosciences
Herstellernummer SPC-964D-DY350
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download