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Rabbit Anti-Human ErbB2 (pTyr877) Polyclonal Dylight 594

Rabbit Anti-Human ErbB2 (pTyr877) Polyclonal Dylight 594
384,49 €
Artikelnummer: STRSPC-969D-DY594

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
Rabbit Anti-Human ErbB2 (pTyr877) Polyclonal Dylight 594

Details

ErbB2 is a receptor-tyrosine kinase of the epidermal growth factor receptor family,that is activated upon binding NRG with ErbB3. NRG acts as an autocrine factor produced in ovarian carcinomas. ERBB2 needs a coreceptor for ligand binding. Activates MAPK and PI3K pathways and is involved in cell proliferation, prolonging and enhancing survival signals, differentiation and apoptosis. Amplification and overexpression of ERBB2 is associated with numerous cancers. The increase of ERBB2 protein in breast tumour can be up to 100-fold.

A 1:250 dilution of SPC-969 was sufficient for detection of ErbB2 (pTyr877) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Zusatzinformation

Artikelnummer STRSPC-969D-DY594
Hersteller Stressmarq Biosciences
Herstellernummer SPC-969D-DY594
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download