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FGFR1 Antibody (pTyr653 + pTyr654): APC/Cy7, Polyclonal

FGFR1 Antibody (pTyr653 + pTyr654): APC/Cy7, Polyclonal
440,15 €
Artikelnummer: STRSPC-981D-APCCY7

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

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FGFR1 Antibody (pTyr653 + pTyr654): APC/Cy7, Polyclonal, Host: Rabbit


Rabbit Anti-Human FGFR1 (pTyr653 + pTyr654) Polyclonal
Target: FGFR1 (pTyr653 + pTyr654)
Purification: Peptide Affinity Purified
Specificity: Detects 91.868 kDa.
Tissue Specificity: Detected in astrocytoma, neuroblastoma and adrenal cortex cell lines.
Conjugate: APC/Cy7
Immunogen Species: Human
Cellular Location: Cell Membrane, Nucleus, Cytoplasm, Cytosol, Cytoplasmic Vesicle
Immunogen: A phospho-specific peptide corresponding to residues surrounding Tyr653 and Tyr654 of human FGFR1 (AA650-657)
Scientific Background: FGFR1 is a receptor-tyrosine kinase that is activated upon binding fibroblast growth factor (FGF). It is a key player in many numerous cell signalling pathways including MAPK/AKT/PLC/STAT/NF-kB. FGF and the FGFR1 is a stimulator of cell differentiation, proliferation, repair, angiogenesis, pro-survival, anti-apoptosis, etc. Overexpression leads to disregulated cell growth which forms the basis of early oncogenesis. This occurs through amplification, gene duplication, or translocation leading to constitutive activation of the receptor.


Artikelnummer STRSPC-981D-APCCY7
Hersteller Stressmarq Biosciences
Herstellernummer SPC-981D-APCCY7
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download