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FGFR1 Antibody (pTyr653 + pTyr654): APC/Cy7, Polyclonal

FGFR1 Antibody (pTyr653 + pTyr654): APC/Cy7, Polyclonal
440,15 €
Artikelnummer: STRSPC-981D-APCCY7

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

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FGFR1 Antibody (pTyr653 + pTyr654): APC/Cy7, Polyclonal, Host: Rabbit

Details

Rabbit Anti-Human FGFR1 (pTyr653 + pTyr654) Polyclonal
Target: FGFR1 (pTyr653 + pTyr654)
Purification: Peptide Affinity Purified
Specificity: Detects 91.868 kDa.
Tissue Specificity: Detected in astrocytoma, neuroblastoma and adrenal cortex cell lines.
Conjugate: APC/Cy7
Immunogen Species: Human
Cellular Location: Cell Membrane, Nucleus, Cytoplasm, Cytosol, Cytoplasmic Vesicle
Immunogen: A phospho-specific peptide corresponding to residues surrounding Tyr653 and Tyr654 of human FGFR1 (AA650-657)
Scientific Background: FGFR1 is a receptor-tyrosine kinase that is activated upon binding fibroblast growth factor (FGF). It is a key player in many numerous cell signalling pathways including MAPK/AKT/PLC/STAT/NF-kB. FGF and the FGFR1 is a stimulator of cell differentiation, proliferation, repair, angiogenesis, pro-survival, anti-apoptosis, etc. Overexpression leads to disregulated cell growth which forms the basis of early oncogenesis. This occurs through amplification, gene duplication, or translocation leading to constitutive activation of the receptor.

Zusatzinformation

Artikelnummer STRSPC-981D-APCCY7
Hersteller Stressmarq Biosciences
Herstellernummer SPC-981D-APCCY7
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download