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Rabbit Anti-Human FGFR2 (pTyr656 + pTyr657) Polyclonal Dylight 594

Rabbit Anti-Human FGFR2 (pTyr656 + pTyr657) Polyclonal Dylight 594
384,49 €
Artikelnummer: STRSPC-982D-DY594

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
Rabbit Anti-Human FGFR2 (pTyr656 + pTyr657) Polyclonal Dylight 594

Details

FGFR2 plays an important role in regulation of cell differentiation, proliferation, migration and apoptosis. It is involved in differentiation and proliferation of osteoblasts and keratinocytes; activates several signalling cascades, such as the MAPK and AKT1 pathway. Missense mutations are associated with ligand independent activation of TK25 (FGFR2) or an activating autocrine signalling loop. Mutations and gene amplifications are involved in various human cancers, and overexpression has been associated with tumourigenesis. Certain missense mutations have been associated with breast, ovarian, endometrial, prostate, bladder, gastric and lung cancers.

A 1:250 dilution of SPC-982 was sufficient for detection of FGFR2 (pTyr656 + pTyr657) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Zusatzinformation

Artikelnummer STRSPC-982D-DY594
Hersteller Stressmarq Biosciences
Herstellernummer SPC-982D-DY594
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download