• Sie sehen derzeit Listenpreise. Um Ihren Vorteilspreis zu sehen, melden Sie sich mit Ihrem Kundenkonto an.

GLUT2 Antibody: Dylight 350, Polyclonal

GLUT2 Antibody: Dylight 350, Polyclonal
378,64 €
Artikelnummer: STRSPC-697D-DY350

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
GLUT2 Antibody: Dylight 350, Polyclonal, Host: Rabbit

Details

Rabbit Anti-Human GLUT2 Polyclonal
Target: GLUT2
Purification: Peptide Affinity Purified
Specificity: Predicted molecular weight at ~57.5kDa. Observed molecular weight at 60-70kDa and 38-45kDa.
Conjugate: Dylight 350
Immunogen Species: Human
Cellular Location: Membrane
Immunogen: Synthetic peptide from the C-terminal of human GLUT2
Scientific Background: Glucose transporter 2 (GLUT2) also known as solute carrier family 2 (facilitated glucose transporter), member 2 (SLC2A2) is a transmembrane carrier protein that enables protein facilitated glucose movement across cell membranes. It is the principal transporter for transfer of glucose between liver and blood, and has a role in renal glucose reabsorption (1). Mutations in SLC2A2 lead to Fanconi-Bickel syndrome (FBS), which results in hepatorenal glycogen accumulation, proximal renal tubular dysfunction, and impaired utilization of glucose and galactose. Recent studies have shown that mutations in SLC2A2 can cause neonatal diabetes, and therefore may contribute to human insulin secretion (2). Novel SLC2A2 mutations have also been discovered and are being investigated to determine their roles in FBS as well (3).
Reference: 1. Kellett G.L., Brot-Laroche E. (2005) Diabetes. 54(10): 3056-3062.2. Sansbury F.H., et al. (2012) Diabetologia. 55(9): 2381-2385.3. Su Z., et al. (2011) J Perdiatr Endocrinol Metab. 24(9-10): 749-753.

Zusatzinformation

Artikelnummer STRSPC-697D-DY350
Hersteller Stressmarq Biosciences
Herstellernummer SPC-697D-DY350
Verpackungseinheit 100 µg
Mengeneinheit FL
Reaktivität Human, Rat (Rattus)
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Immunocytochemistry, Immunofluorescence, Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download