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Rabbit Anti-Human IKKa (pThr179+pSer180) Polyclonal Dylight 633

Rabbit Anti-Human IKKa (pThr179+pSer180) Polyclonal Dylight 633
374,35 €
Artikelnummer: STRSPC-998D-DY633

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

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Rabbit Anti-Human IKKa (pThr179+pSer180) Polyclonal Dylight 633

Details

IKKa is a protein-serine/threonine kinase. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. May play a special role in the immune response. Loss of function therefore blunts the NF-kB response. Cells with DNA damage are unable to undergo apoptosis. Oncogenesis may therefore occur indirectly by inhibitting a downstream tumour suppresor (inhibitors of NF-kB).

A 1:250 dilution of SPC-998 was sufficient for detection of IKKa (pThr179+pSer180) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Zusatzinformation

Artikelnummer STRSPC-998D-DY633
Hersteller Stressmarq Biosciences
Herstellernummer SPC-998D-DY633
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download