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MAP3K8 Antibody (pSer334): Dylight 594, Polyclonal

MAP3K8 Antibody (pSer334): Dylight 594, Polyclonal
401,97 €
Artikelnummer: STRSPC-953D-DY594

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

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MAP3K8 Antibody (pSer334): Dylight 594, Polyclonal, Host: Rabbit

Details

Rabbit Anti-Human MAP3K8 (pSer334) Polyclonal
Target: MAP3K8 (pSer334)
Purification: Peptide Affinity Purified
Specificity: Detects 52.898 kDa.
Tissue Specificity: Expressed in several normal tissues and human tumor-derived cell lines.
Conjugate: Dylight 594
Immunogen Species: Human
Cellular Location: Cytoplasm
Immunogen: A phospho-specific peptide corresponding to residues surrounding Ser334 of human COT (AA331-337)
Scientific Background: MAP3K8 is a protein serine/threonine kinase that can activate both MAPK and JNKK pathways. It is required for TLR4 activation of the MEK/ERK pathway. It can activate NF-kB1 by stimulating the proteolysis of its inhibitor, p105, and promote the production of TNF-alpha and IL-2 during T-cell activation. It has been shown to mediate Raf-inhibiting drug resistance in BRAF(V600E) cell lines. MAP3K8 may also play a role in the cell cycle.

Zusatzinformation

Artikelnummer STRSPC-953D-DY594
Hersteller Stressmarq Biosciences
Herstellernummer SPC-953D-DY594
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download