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MAPK4 Antibody (pSer186): Dylight 488, Polyclonal

MAPK4 Antibody (pSer186): Dylight 488, Polyclonal
397,73 €
Artikelnummer: STRSPC-976D-DY488

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

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MAPK4 Antibody (pSer186): Dylight 488, Polyclonal, Host: Rabbit

Details

Rabbit Anti-Human MAPK4 (pSer186) Polyclonal
Target: MAPK4 (pSer186)
Purification: Peptide Affinity Purified
Specificity: Detects 62.623 kDa.
Tissue Specificity: Highly expressed in heart and brain.
Conjugate: Dylight 488
Immunogen Species: Human
Cellular Location: Cytoplasm, Nucleus
Immunogen: A phospho-specific peptide corresponding to residues surrounding Ser186 of human MAPK4 (AA183-190)
Scientific Background: MAPK4 is a protein-serine/threonine kinase that phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. MAPK4 may promote entry in the cell cycle.

Zusatzinformation

Artikelnummer STRSPC-976D-DY488
Hersteller Stressmarq Biosciences
Herstellernummer SPC-976D-DY488
Verpackungseinheit 100 µl
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Download
MSDS Download