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Rabbit Anti-Human SMAD4 Polyclonal Dylight 594

Rabbit Anti-Human SMAD4 Polyclonal Dylight 594
340,87 €
Artikelnummer: STRSPC-730D-DY594

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
Rabbit Anti-Human SMAD4 Polyclonal Dylight 594

Details

Members of the Smad family of cell signaling molecules are components of a critical intracellular pathway that transmit TGF-β signals from the cell surface into the nucleus. There are three distinct classes of Smads: the receptor-regulated Smads (R-Smads), the common-mediator Smad (co-Smad), and the antagonistic or inhibitory Smads. Following stimulation by TGF-β, Smad2 and Smad3 become phosphorylated at their carboxyl termini (Ser465 and 467 on Smad2; Ser423 and 425 on Smad3) by TGF-β Receptor I. Phosphorylated Smad 2/3 can complex with Smad4, translocate to the nucleus and regulate gene expression.

A 1:1000 dilution of SPC-730 was sufficient for detection of SMAD4 in 15 µg of human HeLa cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Zusatzinformation

Artikelnummer STRSPC-730D-DY594
Hersteller Stressmarq Biosciences
Herstellernummer SPC-730D-DY594
Verpackungseinheit 100 µg
Mengeneinheit FL
Reaktivität Human
Klonalität Polyclonal
Wirt / Host Rabbit
Methode Immunohistochemistry, Western Blotting
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Auf Anfrage
MSDS Download