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GC Globulin, Human Plasma, Mixed Type

GC Globulin, Human Plasma, Mixed Type
647,16 €
Artikelnummer: MOIHGCG-5

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
GC Globulin, Human Plasma, Mixed Type, 5,0 mg

Details

GC globulin, also known as Vitamin D-binding protein (DBP/VDB), Vitamin D-binding protein-macrophage activating factor (DBP-MAF), and Gc protein-derived macrophage activating factor (Gc-MAF), is an alpha 2 glycoprotein composed of a single polypeptide chain and present in plasma at levels of 20-55 mg/100 ml. It functions in the binding and transport of vitamin D and may also play an important role in actin homeostatis since it has been shown to bind monomeric actin with high affinity. GC-globulin also binds membranes of both circulating B and T lymphocytes. Clinically, concentrations are reduced in patients with severe liver diseases. GC-globulin may also play an important role in the mechanism of the osteomalacia that occurs with Itai-Itai disease. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.

Zusatzinformation

Artikelnummer MOIHGCG-5
Hersteller Molecular Innovations
Herstellernummer HGCG-5
Verpackungseinheit 5,0 mg
Mengeneinheit FL
Reaktivität Human
Klonalität Keine Herstellerangabe
Wirt / Host Keine Herstellerangabe
Methode Keine Herstellerangabe
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Auf Anfrage
MSDS Download