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Human CCL17

Human CCL17
953,18 €
Artikelnummer: MOICCL17-0,1

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
Human CCL17, 0,1 mg

Details

C-C motif chemokine 17 (CCL17) is a 71 amino acid Cys-Cys chemokine that plays important roles in T cell development in the thymus as well as in trafficking and activation of mature T cells. It is also known as thymus and activation regulated chemokine (TARC). CCL17 is a ligand for the G protein coupled receptors CCR4 and CCR8, and induces chemotactic migration of T lymphocytes, but not monocytes or granulocytes. CCL17 is expressed at high levels in the thymus and at low levels in the lung, colon and small intestine. CCL17 is induced by phytohemagglutinin in the peripheral blood mononuclear cells and by cytokines in monocytes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC chemokines are chemotactic cytokines characterized by two adjacent cysteines that induce directed chemotaxis in nearby responsive cells.

Zusatzinformation

Artikelnummer MOICCL17-0,1
Hersteller Molecular Innovations
Herstellernummer CCL17-0,1
Verpackungseinheit 0,1 mg
Mengeneinheit FL
Reaktivität Human
Klonalität Keine Herstellerangabe
Wirt / Host Keine Herstellerangabe
Methode Keine Herstellerangabe
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Auf Anfrage
MSDS Download