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Human CCL2

Human CCL2
787,29 €
Artikelnummer: MOICCL2-0,1

Verfügbarkeit: Regellieferzeit: Innerhalb 1 - 2 Wochen

Kostenlose Lieferung innerhalb Österreichs!
Human CCL2, 0,1 mg

Details

C-C motif chemokine 2 (CCL2) is a 76 amino acid Cys-Cys chemokine that has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It is also known as monocyte chemoattractant protein 1 (MCP1), monocyte chemotactic and activating factor (MCAF), and small inducible cytokine A2. CCL2 is a ligand for the G protein coupled receptors CCR2 and CCR4, and induces chemotactic migration of monocytes, activated T cells, basophils, NK cells and dendritic cells, but not neutrophils or eosinophils. CCL2 can augment monocyte anti-tumor activity and may be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC chemokines are chemotactic cytokines characterized by two adjacent cysteines that induce directed chemotaxis in nearby responsive cells.

Zusatzinformation

Artikelnummer MOICCL2-0,1
Hersteller Molecular Innovations
Herstellernummer CCL2-0,1
Verpackungseinheit 0,1 mg
Mengeneinheit FL
Reaktivität Human
Klonalität Keine Herstellerangabe
Wirt / Host Keine Herstellerangabe
Methode Keine Herstellerangabe
Isotype Keine Herstellerangabe
Gene ID NCBI (externer Link)
Datenblatt Auf Anfrage
MSDS Download