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Recombinant Epstein-Barr virus Latent membrane protein 1(LMP1),partial

Recombinant Epstein-Barr virus Latent membrane protein 1(LMP1),partial
1.762,00 €
Artikelnummer: CSB-EP624920EEZ1-1

Verfügbarkeit: Lieferzeit auf Anfrage

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Recombinant Epstein-Barr virus Latent membrane protein 1(LMP1),partial, Host: E.coli

Details

Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. MW: 24.3 kDa. Function: Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular proteins. For example, induces the sumoylation of host IRF7 thereby limiting its transcriptional activity and modulating the activation of innate immune responses. Subcellular Location: Host cell membrane, Multi-pass membrane protein. Protein Families: Herpesviridae LMP-1 family.

Zusatzinformation

Artikelnummer CSB-EP624920EEZ1-1
Hersteller Cusabio
Herstellernummer CSB-EP624920EEZ1-1
Verpackungseinheit 1 mg
Mengeneinheit FL
Reaktivität Epstein-Barr Virus (EBV)
Klonalität Keine Herstellerangabe
Wirt / Host Escherichia Coli
Methode Keine Herstellerangabe
Isotype Keine Herstellerangabe
Gene ID Nein
Datenblatt Auf Anfrage
MSDS Auf Anfrage