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Recombinant Human B-cell receptor CD22(CD22),partial

Recombinant Human B-cell receptor CD22(CD22),partial
576,00 €
Artikelnummer: CSB-MP004900HU-50

Verfügbarkeit: Lieferzeit auf Anfrage

Kostenlose Lieferung innerhalb Österreichs!
Recombinant Human B-cell receptor CD22(CD22),partial, Host: Mammalian cell

Details

Organism: Homo sapiens (Human). Function: Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. Subcellular Location: Cell membrane, Single-pass type I membrane protein. Protein Families: Immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family. Tissue Specificity: B-lymphocytes. Tag Info: C-terminal 6xHis-tagged

Zusatzinformation

Artikelnummer CSB-MP004900HU-50
Hersteller Cusabio
Herstellernummer CSB-MP004900HU-50
Verpackungseinheit 50 µg
Mengeneinheit FL
Reaktivität Keine Herstellerangabe
Klonalität Keine Herstellerangabe
Wirt / Host Mammalian Cell
Methode Keine Herstellerangabe
Isotype Keine Herstellerangabe
Gene ID Nein
Datenblatt Auf Anfrage
MSDS Auf Anfrage