• Sie sehen derzeit Listenpreise. Um Ihren Vorteilspreis zu sehen, melden Sie sich mit Ihrem Kundenkonto an.

Recombinant Human C-C chemokine receptor type 4(CCR4)

Recombinant Human C-C chemokine receptor type 4(CCR4)
1.244,00 €
Artikelnummer: CSB-CF004843HU-100

Verfügbarkeit: Lieferzeit auf Anfrage

Kostenlose Lieferung innerhalb Österreichs!
Recombinant Human C-C chemokine receptor type 4(CCR4), Host: in vitro E.coli expression system

Details

Organism: Homo sapiens (Human). Function: High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. Subcellular Location: Cell membrane, Multi-pass membrane protein. Protein Families: G-protein coupled receptor 1 family. Tissue Specificity: Predominantly expressed in the thymus, in peripheral blood leukocytes, including T-cells, mostly CD4+ cells, and basophils, and in platelets; at lower levels, in the spleen and in monocytes. Detected also in macrophages, IL-2-activated natural killer cells and skin-homing memory T-cells, mostly the ones expressing the cutaneous lymphocyte antigen (CLA). Expressed in brain microvascular and coronary artery endothelial cells. Tag Info: N-terminal 10xHis-tagged

Zusatzinformation

Artikelnummer CSB-CF004843HU-100
Hersteller Cusabio
Herstellernummer CSB-CF004843HU-100
Verpackungseinheit 100 µg
Mengeneinheit FL
Reaktivität Keine Herstellerangabe
Klonalität Keine Herstellerangabe
Wirt / Host Escherichia Coli
Methode Keine Herstellerangabe
Isotype Keine Herstellerangabe
Gene ID Nein
Datenblatt Auf Anfrage
MSDS Auf Anfrage