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Recombinant Human C-C motif chemokine 22 protein(CCL22) (Active)

Recombinant Human C-C motif chemokine 22 protein(CCL22) (Active)
1.711,00 €
Artikelnummer: CSB-AP000951HU-500

Verfügbarkeit: Lieferzeit auf Anfrage

Kostenlose Lieferung innerhalb Österreichs!
Recombinant Human C-C motif chemokine 22 protein(CCL22) (Active), Host: E.Coli

Details

Species: Homo sapiens (Human). Function: May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active. Subcellular Location: Secreted. Protein Families: Intercrine beta (chemokine CC) family. Tissue Specificity: Highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus. Also found in lymph node, appendix, activated monocytes, resting and activated macrophages. Lower expression in lung and spleen. Very weak expression in small intestine. In lymph node expressed in a mature subset of Langerhans' cells (CD1a+ and CD83+). Expressed in Langerhans' cell histiocytosis but not in dermatopathic lymphadenopathy. Expressed in atopic dermatitis, allergic contact dermatitis skin, and psoriasis, in both the epidermis and dermis. Tag Info: Tag-Free.

Zusatzinformation

Artikelnummer CSB-AP000951HU-500
Hersteller Cusabio
Herstellernummer CSB-AP000951HU-500
Verpackungseinheit 500 µg
Mengeneinheit FL
Reaktivität Keine Herstellerangabe
Klonalität Keine Herstellerangabe
Wirt / Host Escherichia Coli
Methode Keine Herstellerangabe
Isotype Keine Herstellerangabe
Gene ID Nein
Datenblatt Auf Anfrage
MSDS Auf Anfrage