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Recombinant Human Epithelial cell adhesion molecule(EPCAM),partial

Recombinant Human Epithelial cell adhesion molecule(EPCAM),partial
788,00 €
Artikelnummer: CSB-EP007717HU-500

Verfügbarkeit: Lieferzeit auf Anfrage

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Recombinant Human Epithelial cell adhesion molecule(EPCAM),partial, Host: E.coli


Tag Info: N-terminal 6xHis-SUMO-tagged. MW: 43.4 kDa. Function: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. Involvement in disease: Diarrhea 5, with tufting enteropathy, congenital (DIAR5); Hereditary non-polyposis colorectal cancer 8 (HNPCC8) . Subcellular Location: Lateral cell membrane, Single-pass type I membrane protein, Cell junction, tight junction.Protein Families: EPCAM family.Tissue Specificity: Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma.


Artikelnummer CSB-EP007717HU-500
Hersteller Cusabio
Herstellernummer CSB-EP007717HU-500
Verpackungseinheit 500 µg
Mengeneinheit FL
Reaktivität Human
Klonalität Keine Herstellerangabe
Wirt / Host Escherichia Coli
Methode Keine Herstellerangabe
Isotype Keine Herstellerangabe
Gene ID Nein
Datenblatt Auf Anfrage
MSDS Auf Anfrage