Recombinant Human Ficolin-3(FCN3)

Tag Info: N-terminal 6xHis-tagged. MW: 34.4 kDa. Function: May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota. Involvement in disease: Ficolin 3 deficiency (FCN3D) . Subcellular Location: Secreted.Protein Families: Ficolin lectin family.Tissue Specificity: Liver and lung. In liver it is produced by bile duct epithelial cells and hepatocytes. In lung it is produced by both ciliated bronchial epithelial cells and type II alveolar epithelial cells.