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Recombinant Human Mucosal addressin cell adhesion molecule 1(MADCAM1),partial

Recombinant Human Mucosal addressin cell adhesion molecule 1(MADCAM1),partial
284,00 €
Artikelnummer: CSB-MP618776HU-10

Verfügbarkeit: Lieferzeit auf Anfrage

Kostenlose Lieferung innerhalb Österreichs!
Recombinant Human Mucosal addressin cell adhesion molecule 1(MADCAM1),partial, Host: Mammalian cell

Details

Organism: Homo sapiens (Human). Function: Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding. Subcellular Location: Membrane, Single-pass type I membrane protein. Tissue Specificity: Highly expressed on high endothelial venules (HEV) and lamina propia venules found in the small intestine, and to a lesser extent in the colon and spleen. Very low levels of expression found in pancreas and brain. Not expressed in the thymus, prostate, ovaries, testis, heart, placenta, lung, liver, skeletal muscle, kidney or peripheral blood leukocytes. Tag Info: N-terminal 10xHis-tagged

Zusatzinformation

Artikelnummer CSB-MP618776HU-10
Hersteller Cusabio
Herstellernummer CSB-MP618776HU-10
Verpackungseinheit 10 µg
Mengeneinheit FL
Reaktivität Human
Klonalität Keine Herstellerangabe
Wirt / Host Mammalian Cell
Methode Keine Herstellerangabe
Isotype Keine Herstellerangabe
Gene ID Nein
Datenblatt Auf Anfrage
MSDS Auf Anfrage